Meningitis is a viral infection caused by the same bacteria that causes the common cold. When contagious disease occurs nearby, it is called meningitis, and the disease is contagious when no symptoms are present (such as in children and the elderly). However, meningitis can also be caused by bacterial meningitis or viral meningitis. Therefore, meningitis diagnostic tests should be done to confirm the presence of meningitis. Although it is a rare disease, cases of meningitis have been on the increase for some time. According to the World Health Organization (WHO), about 5-10% of patients typically die within 24-48 hours of symptom onset despite early diagnosis and adequate treatment. Such a high death rate has increased the demand for meningitis diagnostic tests around the world. It has become imperative that patients with early symptoms be diagnosed immediately and receive the necessary treatment to prevent death.
Since there is a significant loss of life even after receiving treatment, the demand for advanced meningitis diagnostic tools is on the rise. These devices are typically used for sensitive reports and accurate diagnostics, which can potentially save the lives of many people. Meningitis diagnostic tests can be done on patients suspected of having meningitis. Meningitis can affect anyone, regardless of age, sex, sexual activity, or location. Some of the common symptoms of meningitis include fever, mild fever, headache, muscle pain, and stiff neck.
The most reliable method of diagnosing meningitis is by performing a serological test. A serological test, or antibody titer test, is a dosage form of immunoglobulins that detects antibodies against the meningitis virus. These tests are done on samples from the throat or nose of possible cases of meningitis. However, there are also serological tests that can be performed on samples of mucus from the throat of patients. That being said, manufacturers of diagnostic testing devices face strict regulatory compliance, making it difficult for them to bring new products to market. In addition, in emerging economies there is little known about advanced diagnostic laboratories, which may hamper the demand for meningitis diagnostic tests.
Some other promising diagnostic tests for meningitis for adults include polymerase chain reactions (PCR) and transcription-mediated amplification (TMA). Polymerase chain reactions are an efficient method for generating specific DNA fragments which can be used for genetic analysis. TMA involves repeated rounds of DNA strand amplification with restriction enzymes. Although these methods have not yet been widely adopted in clinical practice, they are considered to be cost-effective and reliable for the diagnosis of meningitis in children. The United States reports about 2,600 sporadic cases of bacterial meningitis each year, which explains the high demand for diagnostic tests for meningitis. Recently, in March 2021, Hologic Inc., a medical technology company, acquired Diagenode, a molecular diagnostic company that develops diagnostic tests for meningitis, respiratory diseases, etc., for US $ 159 million.
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